Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins

Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins

The molecular substrate of age-associated cognitive decline (AACD) is still elusive. Evidence indicates that AACD is related to synaptic impairment in hippocampus, but different hippocampal regions play different roles, with the dorsal hippocampus (DH) associated to spatial learning, and the ventral...

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Bibliographic Details
Main Authors: Marta Balietti, Giorgia Fattorini, Arianna Pugliese, Daniele Marcotulli, Luca Bragina, Fiorenzo Conti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
brain aging
cognitive decline
hippocampus
synaptic proteins
synaptotagmin 1
Morris water maze test
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00091/full

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http://journal.frontiersin.org/article/10.3389/fnagi.2018.00091/full

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