Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

The cell surface mucin MUC1 is an important host factor limiting Helicobacter pylori (H. pylori) pathogenesis in both humans and mice by providing a protective barrier and modulating mucosal epithelial and leukocyte responses. The aim of this study was to establish the time-course of molecular event...

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Bibliographic Details
Main Authors: Yong H. Sheng, Garrett Z. Ng, Kim M. Summers, Alison L. Every, Gareth Price, Sumaira Z. Hasnain, Philip Sutton, Michael A. McGuckin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
MUC1
Helicobacter pylori
infection
gene expression
lipid metabolism
SPINK1
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00343/full

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