Melanoma chemotherapy leads to the selection of ABCB5-expressing cells.

Metastatic melanoma is the most aggressive skin cancer. Recently, phenotypically distinct subpopulations of tumor cells were identified. Among them, ABCB5-expressing cells were proposed to display an enhanced tumorigenicity with stem cell-like properties. In addition, ABCB5(+) cells are thought to p...

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Bibliographic Details
Main Authors: Marine Chartrain, Joëlle Riond, Aline Stennevin, Isabelle Vandenberghe, Bruno Gomes, Laurence Lamant, Nicolas Meyer, Jean Edouard Gairin, Nicolas Guilbaud, Jean Philippe Annereau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360047?pdf=render