| Summary: | Computer-Aided Diagnosis (CAD) can improve the accuracy of diagnosis effectively, reduce the rate of misdiagnosis, and provide the support for the valid decision. In clinical applications, high requirements are often imposed on the execution speed and accuracy of CAD systems. The classifier is regarded as the core of the CAD system, that is, the performance of the classifier will have a decisive influence on the operating affection of the CAD system. Extreme Learning Machine (ELM) is a fast learning algorithm using Single Hidden Layer Feedforward Neural Network (SLFN) structure. With its advantages in training speed, generalization performance and accuracy, ELM has draw attention in many research fields, including the development of CAD system. The applications of ELM in CAD are reviewed in this research. First, the mathematical model of ELM and framework of CAD system are briefly introduced. Then, the application of ELM in CAD is reviewed in detail, including the feature modeling method combined with ELM in CAD and the specific application of ELM. Finally, we summarized the current research status of CAD systems based on ELM, and the future work is prospected.
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