Gastric adenocarcinoma in a patient re-infected with <it>H. pylori</it> after regression of MALT lymphoma with successful anti-<it>H. pylori</it> therapy and gastric resection: a case report

• Main Authors: Ghosh Tamal K, Pal Bhaskar B, Ghoshal Ujjala, Chakraborty Srikanta, Pal Chiranjib, Bandyopadhyay Santu, Guha Debashish, Ghoshal Uday C, Banerjee Prabir K
• Format: Article
• Language: English
• Published: BMC 2002-03-01
• Series: BMC Gastroenterology
• Online Access: http://www.biomedcentral.com/1471-230X/2/6

<p>Abstract</p> <p>Background</p> <p><it>Helicobacter pylori (H. pylori)</it> has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patient with <it>H. pylori</it> infection.</p> <p>Case presentation</p> <p>We report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of <it>H. pylori</it> infection. However, he developed GC on follow up; this was temporally associated with recrudescence / re-infection of <it>H. pylori.</it> This is perhaps first report of such occurrence.</p> <p>Conclusions</p> <p>Possible cause and effect relationship between <it>H. pylori</it> infection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with <it>H. pylori</it> is supposed to be high.</p>