Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering

Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering

Reprimo (<i>RPRM</i>) is a tumor suppressor gene involved in the development of gastric cancer. Hypermethylation of the <i>RPRM</i> promoter region has been found in tumor tissue and plasma samples from patients with gastric cancer. These findings suggest that circulating met...

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Bibliographic Details
Main Authors: María José Marchant, Leda Guzmán, Alejandro H. Corvalán, Marcelo J. Kogan
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nanomaterials
Subjects:
gold nanoparticles
methylated <i>RPRM</i> DNA
dynamic light scattering
gastric cancer
noninvasive detection
Online Access:https://www.mdpi.com/2079-4991/9/9/1333

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