A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity

A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity

Essential thrombocytosis (ET) and FV Leiden heterozygosity represent an acquired and hereditable hypercoagulable state, respectively. An uncommon case of coexistence of ET and FV Leiden heterozygosity in a 36-year-old pregnant woman and her successful pregnancy outcome is described. She was consider...

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Main Authors: Marianna Politou, Serena Valsami, Irontianta Gkorezi-Ntavela, Vasilios Telonis, Efrosyni Merkouri, Panagiotis Christopoulos
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2016/7041686
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spelling doaj-47bc5bcd122a4cf8a4278cd77ba6bcc42020-11-24T23:19:46ZengHindawi LimitedCase Reports in Obstetrics and Gynecology2090-66842090-66922016-01-01201610.1155/2016/70416867041686A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden HeterozygosityMarianna Politou0Serena Valsami1Irontianta Gkorezi-Ntavela2Vasilios Telonis3Efrosyni Merkouri4Panagiotis Christopoulos5Blood Transfusion Department, Aretaieion Hospital, National and Kapodistrian Athens University Medical School, 11528 Athens, GreeceBlood Transfusion Department, Aretaieion Hospital, National and Kapodistrian Athens University Medical School, 11528 Athens, GreeceBlood Transfusion Department, Aretaieion Hospital, National and Kapodistrian Athens University Medical School, 11528 Athens, GreeceBlood Transfusion Department, Aretaieion Hospital, National and Kapodistrian Athens University Medical School, 11528 Athens, GreeceCoagulation Laboratory, Iatriko Kentro Hospital, 11525 Athens, Greece2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, National and Kapodistrian Athens University Medical School, 11528 Athens, GreeceEssential thrombocytosis (ET) and FV Leiden heterozygosity represent an acquired and hereditable hypercoagulable state, respectively. An uncommon case of coexistence of ET and FV Leiden heterozygosity in a 36-year-old pregnant woman and her successful pregnancy outcome is described. She was considered to be at high risk of thrombosis during her pregnancy and she was treated with both prophylactic dose of LMWH and aspirin daily throughout her pregnancy and for a 6-week period postpartum. The efficacy of the anticoagulation treatment was monitored in various time points not only by measuring anti-Xa levels and D-Dimers but also with new coagulation methods such as rotation thromboelastometry and multiplate. Global assessment of coagulation using additional newer laboratory tests might prove useful in monitoring coagulation pregnancies at high risk for thrombosis.http://dx.doi.org/10.1155/2016/7041686
collection DOAJ
language English
format Article
sources DOAJ
author Marianna Politou
Serena Valsami
Irontianta Gkorezi-Ntavela
Vasilios Telonis
Efrosyni Merkouri
Panagiotis Christopoulos
spellingShingle Marianna Politou
Serena Valsami
Irontianta Gkorezi-Ntavela
Vasilios Telonis
Efrosyni Merkouri
Panagiotis Christopoulos
A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
Case Reports in Obstetrics and Gynecology
author_facet Marianna Politou
Serena Valsami
Irontianta Gkorezi-Ntavela
Vasilios Telonis
Efrosyni Merkouri
Panagiotis Christopoulos
author_sort Marianna Politou
title A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
title_short A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
title_full A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
title_fullStr A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
title_full_unstemmed A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
title_sort successful mother and neonate outcome for a woman with essential thrombocytosis and fv leiden heterozygosity
publisher Hindawi Limited
series Case Reports in Obstetrics and Gynecology
issn 2090-6684
2090-6692
publishDate 2016-01-01
description Essential thrombocytosis (ET) and FV Leiden heterozygosity represent an acquired and hereditable hypercoagulable state, respectively. An uncommon case of coexistence of ET and FV Leiden heterozygosity in a 36-year-old pregnant woman and her successful pregnancy outcome is described. She was considered to be at high risk of thrombosis during her pregnancy and she was treated with both prophylactic dose of LMWH and aspirin daily throughout her pregnancy and for a 6-week period postpartum. The efficacy of the anticoagulation treatment was monitored in various time points not only by measuring anti-Xa levels and D-Dimers but also with new coagulation methods such as rotation thromboelastometry and multiplate. Global assessment of coagulation using additional newer laboratory tests might prove useful in monitoring coagulation pregnancies at high risk for thrombosis.
url http://dx.doi.org/10.1155/2016/7041686
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