The Potential of the Cyclotide Scaffold for Drug Development

Cyclotides are a novel class of micro-proteins (≈30–40 residues long) with a unique topology containing a head-to-tail cyclized backbone structure further stabilized by three disulfide bonds that form a cystine knot. This unique molecular framework makes them exceptionally stable...

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Bibliographic Details
Main Authors: Julio A. Camarero, Maria Jose Campbell
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomedicines
Subjects:
CCK
Online Access:https://www.mdpi.com/2227-9059/7/2/31