The Potential of the Cyclotide Scaffold for Drug Development
Cyclotides are a novel class of micro-proteins (≈30–40 residues long) with a unique topology containing a head-to-tail cyclized backbone structure further stabilized by three disulfide bonds that form a cystine knot. This unique molecular framework makes them exceptionally stable...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/7/2/31 |