Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)

Background and ObjectivesUnderstanding the pathophysiology of respiratory failure in coronavirus disease 2019 (COVID-19) is indispensable for development of therapeutic strategies. Since we observed similarities between COVID-19 and interstitial lung disease in connective tissue disease (CTD-ILD), w...

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Main Authors: Daniel Gagiannis, Julie Steinestel, Carsten Hackenbroch, Benno Schreiner, Michael Hannemann, Wilhelm Bloch, Vincent G. Umathum, Niklas Gebauer, Conn Rother, Marcel Stahl, Hanno M. Witte, Konrad Steinestel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
connective tissue disease
SARS-CoV-2
coronavirus disease 2019
autoantibodies
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.587517/full

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