Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

Low-density lipoprotein receptor-related protein-1 (LRP1) is a multifunctional uptake receptor for chylomicron remnants in the liver. In vascular smooth muscle cells LRP1 controls reverse cholesterol transport through platelet-derived growth factor receptor β (PDGFR-β) trafficking and tyrosine kinas...

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Bibliographic Details
Main Authors: Yinyuan Ding, Xunde Xian, William L. Holland, Shirling Tsai, Joachim Herz
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:EBioMedicine
Subjects:
Insulin, metabolic syndrome
Insulin resistance
LRP1
Chylomicron remnant
Diabetes
Lipoprotein
PDGF
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416301372

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http://www.sciencedirect.com/science/article/pii/S2352396416301372

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