RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essential for normal gene regulation during development. However, how these systems function to achieve transcriptional regulation remains very poorly understood. Here, we discover that the histone H2AK119...

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Bibliographic Details
Main Authors: Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
chromatin
gene expression
histone modification
Polycomb repressive complex
E3 ubiquitin ligase
Online Access:https://elifesciences.org/articles/18591

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