Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cells.

Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cells.

Under appropriate culture conditions, undifferentiated embryonic stem (ES) cells can undergo multiple self-renewal cycles without loss of pluripotency suggesting they must be equipped with specific defense mechanisms to ensure sufficient genetic stability during self-renewal expansion. The ATP bindi...

Full description

Bibliographic Details
Main Authors: Jimmy Susanto, Yu-Hsing Lin, Yun-Nan Chen, Chia-Rui Shen, Yu-Ting Yan, Sheng-Ta Tsai, Chung-Hsuan Chen, Chia-Ning Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2602981?pdf=render

Internet

http://europepmc.org/articles/PMC2602981?pdf=render

Similar Items