Loss of Non-Apoptotic Role of Caspase-3 in the PINK1 Mouse Model of Parkinson’s Disease

Loss of Non-Apoptotic Role of Caspase-3 in the PINK1 Mouse Model of Parkinson’s Disease

Caspases are a family of conserved cysteine proteases that play key roles in multiple cellular processes, including programmed cell death and inflammation. Recent evidence shows that caspases are also involved in crucial non-apoptotic functions, such as dendrite development, axon pruning, and synapt...

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Bibliographic Details
Main Authors: Paola Imbriani, Annalisa Tassone, Maria Meringolo, Giulia Ponterio, Graziella Madeo, Antonio Pisani, Paola Bonsi, Giuseppina Martella
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
PINK1
caspase-3
striatum
synaptic plasticity
long-term depression
Online Access:https://www.mdpi.com/1422-0067/20/14/3407

Internet

https://www.mdpi.com/1422-0067/20/14/3407

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