Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females

Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females

Abstract Background Mosquito-borne diseases affect millions worldwide, with malaria alone killing over 400 thousand people per year and affecting hundreds of millions. To date, the best strategy to prevent the disease remains insecticide-based mosquito control. However, insecticide resistance as wel...

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Bibliographic Details
Main Authors: Mabel L. Taracena, Catherine M. Hunt, Mark Q. Benedict, Pamela M. Pennington, Ellen M. Dotson
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Parasites & Vectors
Subjects:
Anopheles gambiae
doublesex
RNAi
Gene silencing
Mosquito rearing
Female-specific
Online Access:http://link.springer.com/article/10.1186/s13071-019-3437-4

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