LncRNA PVT1 Mediates Antiapoptosis and 5-Fluorouracil Resistance via Increasing Bcl2 Expression in Gastric Cancer

LncRNA PVT1 Mediates Antiapoptosis and 5-Fluorouracil Resistance via Increasing Bcl2 Expression in Gastric Cancer

Purpose. Plasmacytoma variant translocation 1 (PVT1) is a long noncoding RNA encoded by the human PVT1 gene, which has been verified to mediate tumorigenesis in gastric cancer. However, the underlying molecular mechanisms of PVT1 in gastric cancer (GC) remain largely unknown. Methods. The tumorigeni...

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Bibliographic Details
Main Authors:	Peizhun Du, Cheng’en Hu, Yunyun Qin, Jing Zhao, Rajan Patel, Yan Fu, Mengqi Zhu, Wenhong Zhang, Guangjian Huang
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Journal of Oncology
Online Access:	http://dx.doi.org/10.1155/2019/9325407

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