EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS

EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS

The review describes main classes of extracellular microvesicular particles, mechanisms of their biogenesis and their potential role in the development of tuberculosis. Special attention is paid to apoptosis of macrophages infected with tuberculous mycobacteria, generation of apoptotic ectosome and...

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Main Authors: A. E. Petrenko, Y. Sh. Shvartz, S. N. Belogorodtsev
Format: Article
Language:Russian
Published: NEW TERRA Publishing House 2019-02-01
Series:Tuberkulez i Bolezni Lëgkih
Subjects:
tuberculosis
apoptosis
apoptotic corpuscles
ectosomes
exosomes
Online Access:https://www.tibl-journal.com/jour/article/view/1219
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spelling doaj-477886ca274f440cbbfbfa051fdd7c872021-07-28T20:57:47ZrusNEW TERRA Publishing HouseTuberkulez i Bolezni Lëgkih2075-12302542-15062019-02-01971415110.21292/2075-1230-2019-97-1-41-511219EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSISA. E. Petrenko0Y. Sh. Shvartz1S. N. Belogorodtsev2Novosibirsk Tuberculosis Research Institute; Novosibirsk State UniversityNovosibirsk Tuberculosis Research InstituteNovosibirsk Tuberculosis Research InstituteThe review describes main classes of extracellular microvesicular particles, mechanisms of their biogenesis and their potential role in the development of tuberculosis. Special attention is paid to apoptosis of macrophages infected with tuberculous mycobacteria, generation of apoptotic ectosome and involvement of the latter into the formation of anti-tuberculosis immune response. Conclusion: mechanisms of apoptotic blebbing, ectosomes and clearing of these particles possess the potential to become a new tool within pathogenetic therapy of tuberculosis.https://www.tibl-journal.com/jour/article/view/1219tuberculosisapoptosisapoptotic corpusclesectosomesexosomes
collection DOAJ
language Russian
format Article
sources DOAJ
author A. E. Petrenko
Y. Sh. Shvartz
S. N. Belogorodtsev
spellingShingle A. E. Petrenko
Y. Sh. Shvartz
S. N. Belogorodtsev
EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
Tuberkulez i Bolezni Lëgkih
tuberculosis
apoptosis
apoptotic corpuscles
ectosomes
exosomes
author_facet A. E. Petrenko
Y. Sh. Shvartz
S. N. Belogorodtsev
author_sort A. E. Petrenko
title EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
title_short EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
title_full EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
title_fullStr EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
title_full_unstemmed EXTRACELLULAR MICROVESICULAR PARTICLES IN THE PATHOGENESIS OF TUBERCULOSIS
title_sort extracellular microvesicular particles in the pathogenesis of tuberculosis
publisher NEW TERRA Publishing House
series Tuberkulez i Bolezni Lëgkih
issn 2075-1230
2542-1506
publishDate 2019-02-01
description The review describes main classes of extracellular microvesicular particles, mechanisms of their biogenesis and their potential role in the development of tuberculosis. Special attention is paid to apoptosis of macrophages infected with tuberculous mycobacteria, generation of apoptotic ectosome and involvement of the latter into the formation of anti-tuberculosis immune response. Conclusion: mechanisms of apoptotic blebbing, ectosomes and clearing of these particles possess the potential to become a new tool within pathogenetic therapy of tuberculosis.
topic tuberculosis
apoptosis
apoptotic corpuscles
ectosomes
exosomes
url https://www.tibl-journal.com/jour/article/view/1219
work_keys_str_mv AT aepetrenko extracellularmicrovesicularparticlesinthepathogenesisoftuberculosis
AT yshshvartz extracellularmicrovesicularparticlesinthepathogenesisoftuberculosis
AT snbelogorodtsev extracellularmicrovesicularparticlesinthepathogenesisoftuberculosis
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