Effect of Parkin on methamphetamine‐induced α‐synuclein degradation dysfunction in vitro and in vivo

Effect of Parkin on methamphetamine‐induced α‐synuclein degradation dysfunction in vitro and in vivo

Abstract Introduction Methamphetamine (METH) is a psychostimulant drug with complicated neurotoxicity, and abuse of METH is very common. Studies have shown that METH exposure causes alpha‐synuclein (α‐syn) accumulation. However, the mechanism of α‐syn accumulation has not been determined. Methods In...

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Bibliographic Details
Main Authors: Yunle Meng, Honghua Qiao, Jiuyang Ding, Yitong He, Haoling Fan, Chen Li, Pingming Qiu
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Brain and Behavior
Subjects:
methamphetamine
neurotoxicity
Parkin
α‐syn
Online Access:https://doi.org/10.1002/brb3.1574

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