Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders

Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders

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Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a class of nuclear hormone receptors intimately involved in the regulation of expression of myriad genes that regulate energy metabolism, cell differentiation, apoptosis, and inflammation. Although originally discovered as a piv...

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Main Authors: Ping Ren, Yuquan Zhang, Yan Huang, Yingli Yang, Ming Jiang
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S23527
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spelling doaj-47521893bf274eb5a69b52c438917cd52020-11-25T03:48:09ZengSAGE PublishingClinical Medicine Insights: Oncology1179-55492015-01-01910.4137/CMO.S23527Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic DisordersPing Ren0Yuquan Zhang1Yan Huang2Yingli Yang3Ming Jiang4Department of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.Department of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.Department of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.Department of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.Laboratory of Nuclear Receptors and Cancer Research, Basic Medical Research Center, Nantong University School of Medicine, Nantong, Jiangsu, China.Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a class of nuclear hormone receptors intimately involved in the regulation of expression of myriad genes that regulate energy metabolism, cell differentiation, apoptosis, and inflammation. Although originally discovered as a pivotal regulator of adipocyte differentiation, the roles that PPARγ plays in gynecological disorders are still unknown. There are a number of studies on the functions of PPARγ and its agonists in gynecological disorders. In this mini-review, we provide a brief summary of the advances in recent years.https://doi.org/10.4137/CMO.S23527
collection DOAJ
language English
format Article
sources DOAJ
author Ping Ren
Yuquan Zhang
Yan Huang
Yingli Yang
Ming Jiang
spellingShingle Ping Ren
Yuquan Zhang
Yan Huang
Yingli Yang
Ming Jiang
Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
Clinical Medicine Insights: Oncology
author_facet Ping Ren
Yuquan Zhang
Yan Huang
Yingli Yang
Ming Jiang
author_sort Ping Ren
title Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
title_short Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
title_full Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
title_fullStr Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
title_full_unstemmed Functions of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Gynecologic Disorders
title_sort functions of peroxisome proliferator-activated receptor gamma (pparγ) in gynecologic disorders
publisher SAGE Publishing
series Clinical Medicine Insights: Oncology
issn 1179-5549
publishDate 2015-01-01
description Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of a class of nuclear hormone receptors intimately involved in the regulation of expression of myriad genes that regulate energy metabolism, cell differentiation, apoptosis, and inflammation. Although originally discovered as a pivotal regulator of adipocyte differentiation, the roles that PPARγ plays in gynecological disorders are still unknown. There are a number of studies on the functions of PPARγ and its agonists in gynecological disorders. In this mini-review, we provide a brief summary of the advances in recent years.
url https://doi.org/10.4137/CMO.S23527
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AT yuquanzhang functionsofperoxisomeproliferatoractivatedreceptorgammappargingynecologicdisorders
AT yanhuang functionsofperoxisomeproliferatoractivatedreceptorgammappargingynecologicdisorders
AT yingliyang functionsofperoxisomeproliferatoractivatedreceptorgammappargingynecologicdisorders
AT mingjiang functionsofperoxisomeproliferatoractivatedreceptorgammappargingynecologicdisorders
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