Candida albicans Hyphae: From Growth Initiation to Invasion
Candida albicans is a commensal resident of the human gastrointestinal and genital tracts. Under conditions such as dysbiosis, host immune perturbances, or the presence of catheters/implanted medical devices, the fungus may cause debilitating mucosal or fatal systemic infections. The ability of C. a...
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MDPI AG
2018-01-01
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| Series: | Journal of Fungi |
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| Online Access: | http://www.mdpi.com/2309-608X/4/1/10 |
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doaj-474fb4534a6c402eb7bb8e7ba926a0982020-11-24T21:00:41ZengMDPI AGJournal of Fungi2309-608X2018-01-01411010.3390/jof4010010jof4010010Candida albicans Hyphae: From Growth Initiation to InvasionJigar V. Desai0Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USACandida albicans is a commensal resident of the human gastrointestinal and genital tracts. Under conditions such as dysbiosis, host immune perturbances, or the presence of catheters/implanted medical devices, the fungus may cause debilitating mucosal or fatal systemic infections. The ability of C. albicans to grow as long filamentous hyphae is critical for its pathogenic potential as it allows the fungus to invade the underlying substratum. In this brief review, I will outline the current understanding regarding the mechanistic regulation of hyphal growth and invasion in C. albicans.http://www.mdpi.com/2309-608X/4/1/10Candida albicanshyphaeinvasion |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jigar V. Desai |
| spellingShingle |
Jigar V. Desai Candida albicans Hyphae: From Growth Initiation to Invasion Journal of Fungi Candida albicans hyphae invasion |
| author_facet |
Jigar V. Desai |
| author_sort |
Jigar V. Desai |
| title |
Candida albicans Hyphae: From Growth Initiation to Invasion |
| title_short |
Candida albicans Hyphae: From Growth Initiation to Invasion |
| title_full |
Candida albicans Hyphae: From Growth Initiation to Invasion |
| title_fullStr |
Candida albicans Hyphae: From Growth Initiation to Invasion |
| title_full_unstemmed |
Candida albicans Hyphae: From Growth Initiation to Invasion |
| title_sort |
candida albicans hyphae: from growth initiation to invasion |
| publisher |
MDPI AG |
| series |
Journal of Fungi |
| issn |
2309-608X |
| publishDate |
2018-01-01 |
| description |
Candida albicans is a commensal resident of the human gastrointestinal and genital tracts. Under conditions such as dysbiosis, host immune perturbances, or the presence of catheters/implanted medical devices, the fungus may cause debilitating mucosal or fatal systemic infections. The ability of C. albicans to grow as long filamentous hyphae is critical for its pathogenic potential as it allows the fungus to invade the underlying substratum. In this brief review, I will outline the current understanding regarding the mechanistic regulation of hyphal growth and invasion in C. albicans. |
| topic |
Candida albicans hyphae invasion |
| url |
http://www.mdpi.com/2309-608X/4/1/10 |
| work_keys_str_mv |
AT jigarvdesai candidaalbicanshyphaefromgrowthinitiationtoinvasion |
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1716778897927831552 |