A Case of Infantile Kyrle-Flegel Disease in a 6-Year-Old Yemeni Girl

• Main Authors: Mohammad Ali Alshami, Mona Jameel Mohana
• Format: Article
• Language: English
• Published: Karger Publishers 2016-01-01
• Series: Case Reports in Dermatology
• Subjects: Kyrle disease; Flegel disease; Papule; Keratotic plug; Nodule
• Online Access: http://www.karger.com/Article/FullText/443824

Kyrle disease (KD) and Flegel disease (FD) are rare variants of primary perforating dermatoses, characterized by transepidermal elimination of abnormal endogenous materials. We describe a 6-year-old Yemeni girl with a 2-year history of generalized asymptomatic, small, reddish-brown keratotic papules with a lenticular central keratotic plug. Although these features are synonymous with FD, the histology of a punch biopsy was consistent with KD. The patient was otherwise healthy, and no family members had a history of similar diseases. The patient was diagnosed with KD-FD, owing to the manifestation of features associated with both diseases.