Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

<p>Abstract</p> <p>Background</p> <p>Previous experimental studies concluded that stem cells (SC) may exert their beneficial effects on the ischemic heart by paracrine activation of antiapoptotic pathways. In order to identify potential cardioprotective mediators, we pe...

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Bibliographic Details
Main Authors: Rosenberg Mark, Lutz Matthias, Kühl Constantin, Will Rainer, Eckstein Volker, Krebs Jutta, Katus Hugo A, Frey Norbert
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Translational Medicine
Subjects:
Stem cells
Cardiomyocytes
Apoptosis
Paracrine
Online Access:http://www.translational-medicine.com/content/10/1/115

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