Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant Staphylococcus aureus Infection

Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant Staphylococcus aureus Infection

Methicillin-resistant Staphylococcus aureus (SA) bacteremia is responsible for over 10,000 deaths in the hospital setting each year. Both conventional CD4+ T cells and γδ T cells play protective roles in SA infection through secretion of IFN-γ and IL-17. However, the role of other unconventional T c...

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Bibliographic Details
Main Authors: Samantha Genardi, Lavanya Visvabharathy, Liang Cao, Eva Morgun, Yongyong Cui, Chao Qi, Yi-Hua Chen, Laurent Gapin, Evgeny Berdyshev, Chyung-Ru Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
Staphylococcus aureus
natural killer T cells
CD1
lipid antigens
cytokine
knockout mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.610010/full

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