Fusion Complexes and CD4-independent gp120s for the Induction of HIV-1 Neutralizing Antibodies

Fusion Complexes and CD4-independent gp120s for the Induction of HIV-1 Neutralizing Antibodies

Bibliographic Details
Main Authors:	Lopalco L, Scarlatti G, Ripamonti C, Rossolillo P, Matucci A, Zipeto D, Hazan U, Bertazzoni U
Format:	Article
Language:	English
Published:	BMC 2005-12-01
Series:	Retrovirology

Similar Items

HLA-C increases HIV-1 infectivity and is associated with gp120
by: Beretta Alberto, et al.
Published: (2008-08-01)

HLA-C increases fusion efficiency between the HIV-1 envelope and the cell membrane and is part of the fusion complex
by: Zipeto Donato, et al.
Published: (2006-12-01)

Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4.
by: Samuele E Burastero, et al.
Published: (2011-01-01)

Engineering of HIV gp120 by yeast surface display for neutralizing antibody characterization and immunogen design
by: Mata-Fink, Jordi
Published: (2013)

Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes
by: Nika M. Strokappe, et al.
Published: (2019-06-01)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
by: Hioe Catarina E, et al.
Published: (2008-07-01)

Rapid development of cross-clade neutralizing antibody responses after clade B gp120/gp140 protein priming and clade c gp140 protein boosting
by: Spearman P, et al.
Published: (2012-09-01)

Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120
by: Zhou T, et al.
Published: (2012-09-01)

Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies.
by: Rachel C Doran, et al.
Published: (2018-01-01)

Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies
by: Jennie M. Hutchinson, et al.
Published: (2019-05-01)

Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity.
by: Heidi E Drummer, et al.
Published: (2013-01-01)

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1
by: Suresh C. Raman, et al.
Published: (2019-12-01)

CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies.
by: Hisashi Akiyama, et al.
Published: (2015-03-01)

Geospatial HIV-1 subtype C gp120 sequence diversity and its predicted impact on broadly neutralizing antibody sensitivity.
by: Jyoti Sutar, et al.
Published: (2021-01-01)

Bispecific Anti-HIV Immunoadhesins That Bind Gp120 and Gp41 Have Broad and Potent HIV-Neutralizing Activity
by: Seth H. Pincus, et al.
Published: (2021-07-01)

Characterization of gp120 and Its Single-chain Derivatives, gp120-CD4 and gp120-M9: Implications for Targeting the CD4i Epitope in HIV-1 Vaccine Design
by: Shiver John
Published: (2005-12-01)

Fusion of cytokine and gp120 encoding DNA enhances DNA vaccine immunogenicity
by: Nimal, Sonali
Published: (2004)

A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1.
by: Johannes S Gach, et al.
Published: (2013-01-01)

Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120
by: Matz J, et al.
Published: (2012-09-01)

Correction: CD169-Mediated Trafficking of HIV to Plasma Membrane Invaginations in Dendritic Cells Attenuates Efficacy of Anti-gp120 Broadly Neutralizing Antibodies.
by: PLOS Pathogens Staff
Published: (2015-05-01)

Anti-CD4-gp120 complex antibodies in long-term non-progressors HIV-1 positive patients: a role in slowing disease progression?
by: Pastori Claudia, et al.
Published: (2006-12-01)

Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination
by: Mata-Fink, Jordi, et al.
Published: (2013)

Characterization of a Large Panel of Rabbit Monoclonal Antibodies against HIV-1 gp120 and Isolation of Novel Neutralizing Antibodies against the V3 Loop.
by: Yali Qin, et al.
Published: (2015-01-01)

Role of anti-CD4-binding site antibodies in modulating gp120-specific CD4 T cell and antibody responses
by: Gorny MK, et al.
Published: (2006-12-01)

P04-38. Crystal structure of gp120 in complex with the CD4-binding-site antibody b13 suggests precise targeting is needed for neutralization
by: Kwong PD, et al.
Published: (2009-10-01)

Neutralizing Antibodies Targeting HIV-1 gp41
by: Christophe Caillat, et al.
Published: (2020-10-01)

VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120
by: S. Abigail Smith, et al.
Published: (2019-01-01)

Development of a Stable MGAT1− CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies
by: Rachel C. Doran, et al.
Published: (2018-10-01)

gp120 Immunogen Design And Characterization
by: Chakraborty, Kausik
Published: (2011)

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7.
by: Sakaorat Lertjuthaporn, et al.
Published: (2018-08-01)

Estimated secondary structure propensities within V1/V2 region of HIV gp120 are an important global antibody neutralization sensitivity determinant.
by: Maxim Totrov
Published: (2014-01-01)

The mapping and characterization of a novel binding site on HIV-1 gp120 for the broadly neutralizing monoclonal antibody IgG1 b12
by: Waruk, Jillian
Published: (2011)

The mapping and characterization of a novel binding site on HIV-1 gp120 for the broadly neutralizing monoclonal antibody IgG1 b12
by: Waruk, Jillian
Published: (2011)

Association of enhanced HIV-1 neutralization by a single Y681H substitution in gp41 with increased gp120-CD4 interaction and macrophage infectivity.
by: Rajesh Ringe, et al.
Published: (2012-01-01)

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site
by: Dai K, et al.
Published: (2012-09-01)

Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.
by: S Moses Dennison, et al.
Published: (2011-01-01)

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
by: Jean-Philippe Julien, et al.
Published: (2013-01-01)

Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode.
by: Eric Chabrol, et al.
Published: (2012-01-01)

HIV-1 gp120 : flexibility and glycosylation
by: Kong, Leopold
Published: (2010)

Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.
by: Mei-Yun Zhang, et al.
Published: (2012-01-01)