INFLUENCE OF MAGNETOMICELLS BASED ON IRON NANOPARTICLES COATED BY CARBON ON STRUCTURE OF RAT LIVER

INFLUENCE OF MAGNETOMICELLS BASED ON IRON NANOPARTICLES COATED BY CARBON ON STRUCTURE OF RAT LIVER

In this paper we study the effect of a single intravenous injection of suspension of magnitomitsell based on iron nanoparticles modified with carbon on the structure of the rat liver. Histological examination revealed the hemodynamic disturbances in the stroma of the organ and degenerative changes o...

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Bibliographic Details
Main Authors: G. Yu. Vasyukov, I. V. Milto, I. V. Sukhodolo, I. V. Mitrofanova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2015-04-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
magnitomicelles
iron nanoparticles
surface modification
perls-positive macrophages
morphology
Online Access:https://bulletin.tomsk.ru/jour/article/view/125
Description
Summary:In this paper we study the effect of a single intravenous injection of suspension of magnitomitsell based on iron nanoparticles modified with carbon on the structure of the rat liver. Histological examination revealed the hemodynamic disturbances in the stroma of the organ and degenerative changes of hepatocytes from 1 to 40 days of the experiment. Perls histochemical reaction demonstrated the accumulation of modified iron nanoparticles in cells of the mononuclear phagocyte system of the liver. Number of Perlspositive macrophages decreased during the experiment from 1 to 40 per day.
ISSN:1682-0363
1819-3684

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