| Summary: | The compounds bis(4,6-dichloro/bis[(p-methoxyphenyl)amino]-1,3,5--triazin-2-yl)1,2-hydrazine-1,2-dicarbodithioate/1,4-phenylenebis(carbamodithioate)/(1,1’-biphenyl)-4,4’-diylbis(carbamodithioate)/(sulphonyldi-4,1-phenylene)-bis(carbamodithioate/1,2-ethanediylbis(carbamothioate) 4a–j were synthesized by two different methods. In the first method (A) for the preparation of 4a–e, 2,4,6-trichloro-1,3,5-triazine 1 was condensed with diammonium 1,2-hydrazine-1,2-dicarbodithioate/1,4-phenylenebis(carbamodithioate)/(1,1’-biphenyl)-4,4’diylbis(carbamodithioate)/(sulphonyl-di-4,1-phenylene)-bis(carbamodithioate)/1,2-ethanediylbis(carbamodithioate) 3a–e to afford 4a–e which undergo reaction with p-methoxyaniline to afford 4f–j. In the second method (B) of preparation, 1 was condensed with p-methoxyaniline to yield 2 followed by the action of 3a–e to yield 4a–j. The structure of the newly synthesized compounds 4a–j was established on the basis of elemental analyses, as well as IR and 1H-NMR spectroscopy. The antimicrobial activities of compounds 4a–j were determined by the cup‑plate method against gram-positive bacteria, gram-negative bacteria and fungi. All the synthesized compounds showed significant antimicrobial activity.
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