Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression
Membrane-anchored DNA probes have been used to study molecular interactions and control cell assembly, but are not selective for different cell membranes. Here the authors develop a lipid-conjugated oligonucleotide for alkaline phosphatase-dependent cell membrane anchorage and use it to distinguish...
Main Authors: | Cheng Jin, Jiaxuan He, Jianmei Zou, Wenjing Xuan, Ting Fu, Ruowen Wang, Weihong Tan |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10639-6 |
Similar Items
-
Biocompatibility and Alkaline Phosphatase Activity of Phosphorylated Chitooligosaccharides on the Osteosarcoma MG63 Cell Line
by: Jayachandran Venkatesan, et al.
Published: (2010-10-01) -
Studies of the characteristics and function of some membrane-bound alkaline phosphatases
by: Rahbani-Nobar, M.
Published: (1978) -
Synthesis of Oligonucleotide Conjugates and Phosphorylated Nucleotide Analogues: An Improvement to a Solid Phase Synthetic Approach
by: Valeria Romanucci, et al.
Published: (2013-01-01) -
The role played by alkaline phosphatase in lipid droplet formation in different lipid-storing cell types
by: Chirambo, George Malipa
Published: (2013) -
Immobilization of alkaline phosphatase on microporous chitosan membranes for bone tissue engineering
by: Wen-chun Hsieh, et al.
Published: (2011)