Genome-wide screen of genes required for caffeine tolerance in fission yeast.

<h4>Background</h4>An excess of caffeine is cytotoxic to all eukaryotic cell types. We aim to study how cells become tolerant to a toxic dose of this drug, and the relationship between caffeine and oxidative stress pathways.<h4>Methodology/principal findings</h4>We searched f...

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Main Authors: Isabel A Calvo, Natalia Gabrielli, Iván Iglesias-Baena, Sarela García-Santamarina, Kwang-Lae Hoe, Dong Uk Kim, Miriam Sansó, Alice Zuin, Pilar Pérez, José Ayté, Elena Hidalgo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19672306/pdf/?tool=EBI