Positive and negative regulation of prostate stem cell antigen expression by Yin Yang 1 in prostate epithelial cell lines.

Prostate cancer is influenced by epigenetic modification of genes involved in cancer development and progression. Increased expression of Prostate Stem Cell Antigen (PSCA) is correlated with development of malignant human prostate cancer, while studies in mouse models suggest that decreased PSCA lev...

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Bibliographic Details
Main Authors: Shuai Tang, Meenu Mishra, Donna P Frazier, Miranda L Moore, Kazushi Inoue, Rajendar Deora, Guangchao Sui, Purnima Dubey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3334921?pdf=render