Global Methylation and Hydroxymethylation in DNA from Blood and Saliva in Healthy Volunteers

Global Methylation and Hydroxymethylation in DNA from Blood and Saliva in Healthy Volunteers

Aims. We describe a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify and compare simultaneously global methylation and hydroxymethylation in human DNA of different tissues. Materials and Methods. Blood and saliva DNA from fourteen volunteers was processed for epigenetic e...

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Bibliographic Details
Main Authors:	Lode Godderis, Caroline Schouteden, Ali Tabish, Katrien Poels, Peter Hoet, Andrea A. Baccarelli, Kirsten Van Landuyt
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2015/845041

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