Replication-Independent Generation and Morphological Analysis of Flavivirus Replication Organelles

Replication-Independent Generation and Morphological Analysis of Flavivirus Replication Organelles

Summary: Positive-strand RNA viruses replicate in distinct membranous structures called replication organelles (ROs). Mechanistic studies of RO formation have been difficult because perturbations affecting viral replication have an impact on viral protein amounts, thus affecting RO biogenesis. Here,...

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Bibliographic Details
Main Authors: Sarah Goellner, Berati Cerikan, Mirko Cortese, Christopher J. Neufeldt, Uta Haselmann, Ralf Bartenschlager
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:STAR Protocols
Subjects:
Cell Biology
Microscopy
Molecular Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672030160X

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