Trastuzumab-Coated Nanoparticles Loaded With Docetaxel for Breast Cancer Therapy

Trastuzumab-Coated Nanoparticles Loaded With Docetaxel for Breast Cancer Therapy

Docetaxel (DTX) is commonly used for breast cancer treatment. Tween 80 used for DTX dissolution in its clinical formulation causes severe hypersensitivity and other adverse reactions. In this study, trastuzumab (Tmab)-coated lipid-polymer hybrid nanoparticles (PLNs) were prepared, composed of poly (...

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Bibliographic Details
Main Authors: Xueyan Zhang, Jiaxin Liu, Xiangyu Li, Fang Li, Robert J. Lee, Fengying Sun, Youxin Li, Zongyu Liu, Lesheng Teng
Format: Article
Language:English
Published: SAGE Publishing 2019-09-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325819872583

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