Effects of Sorafenib, a Tyrosin Kinase Inhibitor, on Adrenocortical Cancer

Effects of Sorafenib, a Tyrosin Kinase Inhibitor, on Adrenocortical Cancer

The lack of an effective medical treatment for adrenocortical carcinoma (ACC) has prompted the search for better treatment protocols for ACC neoplasms. Sorafenib, a tyrosine kinase inhibitor has exhibited effectiveness in the treatment of different human tumors. Therefore, the aim of this study was...

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Bibliographic Details
Main Authors: Lidia Cerquetti, Barbara Bucci, Salvatore Raffa, Donatella Amendola, Roberta Maggio, Pina Lardo, Elisa Petrangeli, Maria Rosaria Torrisi, Vincenzo Toscano, Giuseppe Pugliese, Antonio Stigliano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Endocrinology
Subjects:
adrenal cancer
neoangiogenesis
sorafenib
apoptosis
intercellular junctions
spheroids
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.667798/full

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