Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively translating. Therefore, we imaged single β-actin m...

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Bibliographic Details
Main Authors:	Zachary B Katz, Brian P English, Timothée Lionnet, Young J Yoon, Nilah Monnier, Ben Ovryn, Mark Bathe, Robert H Singer
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2016-01-01
Series:	eLife
Subjects:	cell motility focal adhesion single molecule tracking translation mRNA localization
Online Access:	https://elifesciences.org/articles/10415

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