Increased ABCC4 Expression Induced by ERRα Leads to Docetaxel Resistance via Efflux of Docetaxel in Prostate Cancer

Increased ABCC4 Expression Induced by ERRα Leads to Docetaxel Resistance via Efflux of Docetaxel in Prostate Cancer

Docetaxel is a major treatment for advanced prostate cancer (PCa); however, its resistance compromises clinical effectiveness. Estrogen receptor-related receptor alpha (ERRα) belongs to an orphan nuclear receptor superfamily and was recently found to be closely involved in cancer. In the present stu...

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Bibliographic Details
Main Authors: Houbao Huang, Jing Li, Jing Shen, Ling Lin, Xu Wu, Shixin Xiang, Yawei Li, Yujie Xu, Qijie Zhao, Yueshui Zhao, Parham Jabbarzadeh Kaboli, Mingxing Li, Xiang Li, Weiping Wang, Qinglian Wen, Zhangang Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
docetaxel resistance
ERRα
ABCC4
bioinformatics
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01474/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01474/full

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