Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors

Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors

Despite considerable efforts, therapeutic strategies targeting the Wnt pathway are still not clinically available. The pervasive role of Wnt‐βcatenin signaling for the control of stem cells during normal tissue homeostasis makes the on‐target toxicity of available therapeutic grade molecules an impo...

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Bibliographic Details
Main Author:	Stephane Angers
Format:	Article
Language:	English
Published:	Wiley 2021-04-01
Series:	EMBO Molecular Medicine
Online Access:	https://doi.org/10.15252/emmm.202114002

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