Irbesartan ameliorates chronic mountain sickness in a rat model via the cholesterol metabolism: An iTRAQ -based proteomics analysis

Irbesartan ameliorates chronic mountain sickness in a rat model via the cholesterol metabolism: An iTRAQ -based proteomics analysis

Objective: To study the effects of irbesartan on pulmonary artery lesions in a rat model with chronic mountain sickness (CMS) and identify the biomarkers involved. Methods: In this study, we used a rat model of CMS to evaluate the therapeutic effect of irbesartan by measuring pulmonary artery pressu...

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Bibliographic Details
Main Authors:	Yiliyaer Nijiati, Tao Yang, Mutalifu Aimaiti, Dilinuer Maimaitiyiming, Ainiwaer Aikemu
Format:	Article
Language:	English
Published:	Elsevier 2021-09-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Chronic mountain sickness Irbesartan ITRAQ-based proteomics Biomarkers Cholesterol Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332221005849

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