The use of ex vivo ovary culture for assessment of alterations in steroidogenesis following neonatal exposure to poly(ethylene glycol)-block-polylactide methyl ether or titanium dioxide nanoparticles in Wistar rats

The use of ex vivo ovary culture for assessment of alterations in steroidogenesis following neonatal exposure to poly(ethylene glycol)-block-polylactide methyl ether or titanium dioxide nanoparticles in Wistar rats

Objectives. Rapid development and widespread application of different types of nanoparticles (NPs) may result in increased exposure of humans and animals to NPs. Recently, reproductive toxicity due to NP exposure has become a major component of risk assessment. Current data have suggested that NPs m...

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Bibliographic Details
Main Authors: Scsukova Sona, Mlynarcikova Alzbeta Bujnakova, Rollerova Eva
Format: Article
Language:English
Published: Sciendo 2020-01-01
Series:Endocrine Regulations
Subjects:
polymeric nanoparticles
peg-b-pla
titanium dioxide
ovary
progesterone
estradiol
reproductive toxicity
Online Access:https://doi.org/10.2478/enr-2020-0007

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