TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity

TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity

Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL/TNFSF10) and Fas Ligand (FasL/TNFSF6), two major cytokines of the TNF (Tumor Necrosis Factor) superfamily, exert their main functions from the immune system compartment. Mice model studies revealed that TRAIL and FasL-mediated signalling...

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Bibliographic Details
Main Authors: Aurélie Rossin, Giorgia Miloro, Anne-Odile Hueber
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
death receptors
autoimmunity
cancer
immune system
cell death
Online Access:https://www.mdpi.com/2072-6694/11/5/639

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