Interferon-α reduces the gefitinib sensitivity of human non-small cell lung cancer

Interferon-α reduces the gefitinib sensitivity of human non-small cell lung cancer

Aim of the study : Many studies have shown that interferon-α(IFN-α) enhances the antiproliferative effect of gefitinib in some solid tumours. We aimed to determine the effect of combining IFN-αwith gefitinib in human non-small cell lung cancer (NSCLC) cell lines (A549, H1299, HCC827) with differen...

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Bibliographic Details
Main Authors: Chi Pan, Shanshan Weng, Yin Duan, Ling Ding, Suzhan Zhang, Jianjin Huang
Format: Article
Language:English
Published: Termedia Publishing House 2016-09-01
Series:Contemporary Oncology
Subjects:
interferon-α
gefitinib
antagonism
non-small cell lung cancer
STAT3
Online Access:https://www.termedia.pl/Interferon-reduces-the-gefitinib-sensitivity-of-human-non-small-cell-lung-cancer,3,28193,1,1.html

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