MYOCARDIAL INFARCTION AND STROKE: 16-YEAR RISK AND STRESS AT WORK IN OPEN POPULATION OF 25–64-YEAR-OLD WOMEN IN RUSSIA/SIBERIA (WHO MONICA–PSYCHOSOCIAL PROGRAM)

• Main Authors: V. Gafarov, D. Panov, E. Gromova, I. Gagulin, A. Gafarova
• Format: Article
• Language: Russian
• Published: «FIRMA «SILICEA» LLC 2016-04-01
• Series: Российский кардиологический журнал
• Subjects: cardiology; myocardial infarction; stroke; stress at workplace; hazard ratio; social gradient
• Online Access: https://russjcardiol.elpub.ru/jour/article/view/647
• ISSN: 1560-4071; 2618-7620

Aim. To determine the effects of stress at workplace on the risks (HR: hazard ratio) of development of myocardial infarction and stroke in open population of 25-64-yearold women in Russia/Siberia (Novosibirsk).Material and methods. Random representative sample of 25-64-year-old women (n=870) was examined in a framework of WHO MONICA-Psychosocial program in one of Novosibirsk districts. Stress at workplace was studied by using the Karasek scale; attitudes to work and prophylactic exams were studied by using the scale of “Knowledge and attitude towards one’s own health” of WHO MONICA-Psychosocial program. During 16 years (1994-2010), all first-time cases of myocardial infarction and stroke were studied in the cohort based on the WHO program of Register of Acute Myocardial Infarction and all available documentation. Cox regression model was used for determination of myocardial infarction and stroke risk over 16 years of follow-up.Results. Prevalence rate of high level of stress in open population of 25-64-yearold women was 31,6%. High levels of stress at work were associated with high levels of responsibility, inability to get rest at the end of workday, frequent professional dissatisfaction, and decreased working ability. For 16 years, HR was by 3,22 times higher for myocardial infarction (p<0,05) and 1,96 times higher for stroke (p<0,05) in women with stress at work. Rates of myocardial infarction and stroke were higher in married women who experienced stress at work, belonged to categories of managers and physical labor, and had high and low level of education.Conclusion. Prevalence of high level of stress at workplace is significant in open population of 25–64-year-old women in Russia/Siberia (Novosibirsk). In the presence of stress at workplace, HR of myocardial infarction and stroke were 2 to 3 times higher than without it. Social gradient affected HR of infarct and stroke.