Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro.

The human hair follicle is a neuroendocrine mini-organ that can be used to study aging processes in vitro. Neurotrophins maintain homeostasis in hair biology via the Trk-family of receptors. TrkA, the high affinity receptor for nerve growth factor (NGF), is expressed in hair follicle melanocytes and...

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Bibliographic Details
Main Authors: Remo Campiche, Maria Daniltchenko, Dominik Imfeld, Eva M J Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221757