Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b

Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b

Tumour cells release large quantities of extracellular vesicles (EVs) to mediate their interactions with other cells in the tumour microenvironment. To identify host cells that naturally take up EVs from tumour cells, we created breast cancer cell lines secreting fluorescent EVs. These fluorescent E...

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Bibliographic Details
Main Authors: Luyen Tien Vu, Boya Peng, Daniel Xin Zhang, Victor Ma, Camille A. Mathey-Andrews, Chun Kuen Lam, Theodoros Kiomourtzis, Jingmin Jin, Larry McReynolds, Linfeng Huang, Andrew Grimson, William C. Cho, Judy Lieberman, Minh Tn Le
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
micrornas
cancer-associated fibroblasts
breast cancer
Online Access:http://dx.doi.org/10.1080/20013078.2019.1599680

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