Increased p63 expression in canine perianal gland tumours
p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine peria...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2018-07-01
|
Series: | Journal of Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.2478/jvetres-2018-0020 |
id |
doaj-46a88abe2a3c49d0818ef561f80872bf |
---|---|
record_format |
Article |
spelling |
doaj-46a88abe2a3c49d0818ef561f80872bf2021-09-06T19:41:49ZengSciendoJournal of Veterinary Research2450-86082018-07-0162222923510.2478/jvetres-2018-0020jvetres-2018-0020Increased p63 expression in canine perianal gland tumoursKim Soo-Hyeon0Seung Byung-Joon1Cho Seung-Hee2Lim Ha-Young3Park Hee-Myung4Sur Jung-Hyang5Small Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of Koreap63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas.https://doi.org/10.2478/jvetres-2018-0020dogperianal gland tumourp63immunohistochemistry |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kim Soo-Hyeon Seung Byung-Joon Cho Seung-Hee Lim Ha-Young Park Hee-Myung Sur Jung-Hyang |
spellingShingle |
Kim Soo-Hyeon Seung Byung-Joon Cho Seung-Hee Lim Ha-Young Park Hee-Myung Sur Jung-Hyang Increased p63 expression in canine perianal gland tumours Journal of Veterinary Research dog perianal gland tumour p63 immunohistochemistry |
author_facet |
Kim Soo-Hyeon Seung Byung-Joon Cho Seung-Hee Lim Ha-Young Park Hee-Myung Sur Jung-Hyang |
author_sort |
Kim Soo-Hyeon |
title |
Increased p63 expression in canine perianal gland tumours |
title_short |
Increased p63 expression in canine perianal gland tumours |
title_full |
Increased p63 expression in canine perianal gland tumours |
title_fullStr |
Increased p63 expression in canine perianal gland tumours |
title_full_unstemmed |
Increased p63 expression in canine perianal gland tumours |
title_sort |
increased p63 expression in canine perianal gland tumours |
publisher |
Sciendo |
series |
Journal of Veterinary Research |
issn |
2450-8608 |
publishDate |
2018-07-01 |
description |
p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas. |
topic |
dog perianal gland tumour p63 immunohistochemistry |
url |
https://doi.org/10.2478/jvetres-2018-0020 |
work_keys_str_mv |
AT kimsoohyeon increasedp63expressionincanineperianalglandtumours AT seungbyungjoon increasedp63expressionincanineperianalglandtumours AT choseunghee increasedp63expressionincanineperianalglandtumours AT limhayoung increasedp63expressionincanineperianalglandtumours AT parkheemyung increasedp63expressionincanineperianalglandtumours AT surjunghyang increasedp63expressionincanineperianalglandtumours |
_version_ |
1717765333572386816 |