Increased p63 expression in canine perianal gland tumours

p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine peria...

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Main Authors: Kim Soo-Hyeon, Seung Byung-Joon, Cho Seung-Hee, Lim Ha-Young, Park Hee-Myung, Sur Jung-Hyang
Format: Article
Language:English
Published: Sciendo 2018-07-01
Series:Journal of Veterinary Research
Subjects:
dog
p63
Online Access:https://doi.org/10.2478/jvetres-2018-0020
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spelling doaj-46a88abe2a3c49d0818ef561f80872bf2021-09-06T19:41:49ZengSciendoJournal of Veterinary Research2450-86082018-07-0162222923510.2478/jvetres-2018-0020jvetres-2018-0020Increased p63 expression in canine perianal gland tumoursKim Soo-Hyeon0Seung Byung-Joon1Cho Seung-Hee2Lim Ha-Young3Park Hee-Myung4Sur Jung-Hyang5Small Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of KoreaDepartment of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, 05029, Seoul, Republic of KoreaSmall Animal Tumour Diagnostic Centre, Department of Veterinary Pathology, Konkuk University, 05029, Seoul, Republic of Koreap63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas.https://doi.org/10.2478/jvetres-2018-0020dogperianal gland tumourp63immunohistochemistry
collection DOAJ
language English
format Article
sources DOAJ
author Kim Soo-Hyeon
Seung Byung-Joon
Cho Seung-Hee
Lim Ha-Young
Park Hee-Myung
Sur Jung-Hyang
spellingShingle Kim Soo-Hyeon
Seung Byung-Joon
Cho Seung-Hee
Lim Ha-Young
Park Hee-Myung
Sur Jung-Hyang
Increased p63 expression in canine perianal gland tumours
Journal of Veterinary Research
dog
perianal gland tumour
p63
immunohistochemistry
author_facet Kim Soo-Hyeon
Seung Byung-Joon
Cho Seung-Hee
Lim Ha-Young
Park Hee-Myung
Sur Jung-Hyang
author_sort Kim Soo-Hyeon
title Increased p63 expression in canine perianal gland tumours
title_short Increased p63 expression in canine perianal gland tumours
title_full Increased p63 expression in canine perianal gland tumours
title_fullStr Increased p63 expression in canine perianal gland tumours
title_full_unstemmed Increased p63 expression in canine perianal gland tumours
title_sort increased p63 expression in canine perianal gland tumours
publisher Sciendo
series Journal of Veterinary Research
issn 2450-8608
publishDate 2018-07-01
description p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas.
topic dog
perianal gland tumour
p63
immunohistochemistry
url https://doi.org/10.2478/jvetres-2018-0020
work_keys_str_mv AT kimsoohyeon increasedp63expressionincanineperianalglandtumours
AT seungbyungjoon increasedp63expressionincanineperianalglandtumours
AT choseunghee increasedp63expressionincanineperianalglandtumours
AT limhayoung increasedp63expressionincanineperianalglandtumours
AT parkheemyung increasedp63expressionincanineperianalglandtumours
AT surjunghyang increasedp63expressionincanineperianalglandtumours
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