Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis
In breast cancer, the loss of expression of WW domain-containing oxireductase (Wwox) has been observed. Here, the authors illustrate that in triple negative breast cancer models Wwox suppresses metastasis and proliferation via the JAK2/STAT3 pathway.
Bibliographic Details
| Main Authors: |
Renxu Chang,
Lele Song,
Yi Xu,
Yanjun Wu,
Cheng Dai,
Xinyu Wang,
Xia Sun,
Yingyong Hou,
Wei Li,
Xianbao Zhan,
Lixing Zhan |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2018-08-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-018-05852-8
|
|---|
