Associations of [18F]-APN-1607 Tau PET Binding in the Brain of Alzheimer’s Disease Patients With Cognition and Glucose Metabolism

Associations of [18F]-APN-1607 Tau PET Binding in the Brain of Alzheimer’s Disease Patients With Cognition and Glucose Metabolism

Molecular imaging of tauopathies is complicated by the differing specificities and off-target binding properties of available radioligands for positron emission tomography (PET). [18F]-APN-1607 ([18F]-PM-PBB3) is a newly developed PET tracer with promising properties for tau imaging. We aimed to cha...

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Bibliographic Details
Main Authors: Jiaying Lu, Weiqi Bao, Ming Li, Ling Li, Zhengwei Zhang, Ian Alberts, Matthias Brendel, Paul Cumming, Huimeng Lu, Zhenxu Xiao, Chuantao Zuo, Yihui Guan, Qianhua Zhao, Axel Rominger
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
tau
neurodegeneration
metabolism
cognition
Alzheimer’s disease
positron emission tomography
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00604/full

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