THP-1 macrophages and SGBS adipocytes - a new human in vitro model system of inflamed adipose tissue

THP-1 macrophages and SGBS adipocytes - a new human in vitro model system of inflamed adipose tissue

Obesity is associated with an accumulation of macrophages in adipose tissue. This inflammation of adipose tissue is a key event in the pathogenesis of several obesity-related disorders, particularly insulin resistance.Here, we summarized existing model systems that mimic the situation of inflamed ad...

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Bibliographic Details
Main Authors: Michaela eKeuper, Anna eDzyakanchuk, Kurt E Amrein, Martin eWabitsch, Pamela eFischer-Posovszky
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Endocrinology
Subjects:
Adipocytes
Macrophages
adipose tissue inflammation
SGBS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00089/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00089/full

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