A Low Glycaemic Index Diet in Pregnancy Induces DNA Methylation Variation in Blood of Newborns: Results from the ROLO Randomised Controlled Trial

A Low Glycaemic Index Diet in Pregnancy Induces DNA Methylation Variation in Blood of Newborns: Results from the ROLO Randomised Controlled Trial

The epigenetic profile of the developing fetus is sensitive to environmental influence. Maternal diet has been shown to influence DNA methylation patterns in offspring, but research in humans is limited. We investigated the impact of a low glycaemic index dietary intervention during pregnancy on off...

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Bibliographic Details
Main Authors: Aisling A. Geraghty, Alexandra Sexton-Oates, Eileen C. O’Brien, Goiuri Alberdi, Peter Fransquet, Richard Saffery, Fionnuala M. McAuliffe
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Nutrients
Subjects:
epigenetics
DNA methylation
programming
methylome
fetus
pregnancy
intervention
diet
glycaemic index
Online Access:http://www.mdpi.com/2072-6643/10/4/455

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