Clusterin Reduces Cold Ischemia-Reperfusion Injury in Heart Transplantation Through Regulation of NF-kB Signaling and Bax/Bcl-xL Expression

Clusterin Reduces Cold Ischemia-Reperfusion Injury in Heart Transplantation Through Regulation of NF-kB Signaling and Bax/Bcl-xL Expression

Background/Aims: Ischemia-reperfusion (I/R) injury is an unavoidable event occurring during heart transplantation and is a key factor in graft failure and the long-term survival rate of recipients. Therefore, there is an urgent need for the development of new therapies to prevent I/R injury. Cluster...

Full description

Bibliographic Details
Main Authors: Guodong Liu, Hongmei Zhang, Fengyun Hao, Jing Hao, Lixiao Pan, Qing Zhao, Jinshan Wo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ischemia reperfusion injury
Heart transplantation
Clusterin
NF-κB
Bax
Bcl-xL
Online Access:https://www.karger.com/Article/FullText/487295

Internet

https://www.karger.com/Article/FullText/487295

Similar Items