Key role of local regulation in chemosensing revealed by a new molecular interaction-based modeling method.
The signaling network underlying eukaryotic chemosensing is a complex combination of receptor-mediated transmembrane signals, lipid modifications, protein translocations, and differential activation/deactivation of membrane-bound and cytosolic components. As such, it provides particularly interestin...
Main Authors: | Martin Meier-Schellersheim, Xuehua Xu, Bastian Angermann, Eric J Kunkel, Tian Jin, Ronald N Germain |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-07-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.0020082 |
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