Combination hyperbaric oxygen and temozolomide therapy in c6 rat glioma model Terapia combinada de oxigênio hiperbárico e temozomida no modelo C6 de glioma em ratos

PURPOSE: Temozolomide (TMZ) has anti-tumor activity in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are limited because of the hypoxic tumor microenvironment. We examined the combined effects of TMZ-HBO in a rat glioma model. METHODS: Aft...

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Bibliographic Details
Main Authors: Yaşar Dagıstan, Ismail Karaca, Erol Ruştu Bozkurt, Engin Ozar, Kaan Yagmurlu, Akin Toklu, Ayhan Bilir
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2012-06-01
Series:Acta Cirurgica Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000600005